The Best Supplements for Adrenal Support: Naturally Reclaim Your Energy

In our fast-paced, high-stress world, adrenal fatigue is more than just a buzzword — it’s a signal from your body that it’s overwhelmed and under-supported. Your adrenal glands, two small glands that sit above your kidneys, play a vital role in managing stress by producing hormones like cortisol, adrenaline, and DHEA.

When chronic stress hits, your adrenals can become depleted — leading to symptoms like low energy, brain fog, trouble sleeping, irritability, and even sugar cravings. If that sounds familiar, it may be time to show your adrenals some love.

Here are the top supplements for adrenal support that can help restore balance and boost your resilience naturally: (post includes affiliate links; full disclosure statement available {here})

Adaptogenic Herbs

Adaptogens are nature’s stress soothers — they help your body adapt to physical, mental, and emotional stress.

• Ashwagandha: Balances cortisol, reduces anxiety, and supports sleep
• Rhodiola rosea: Enhances stamina and focus while reducing burnout
• Holy basil: Calms the nervous system and helps stabilize blood sugar
• Eleuthero (Siberian ginseng): Increases endurance and immune resilience

Best taken in the morning or early afternoon to support natural energy cycles.

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 Vitamin C

Your adrenal glands are one of the highest concentrations of vitamin C in the body. During times of stress, your vitamin C needs go up dramatically.

• Supports adrenal hormone production
• Protects adrenal tissues from oxidative stress
• Helps with recovery from burnout

 Recommended dose: 500–2000 mg/day (split doses for better absorption)

 

B Vitamins (Especially B5, B6 & B12)

The B-complex vitamins are essential for energy metabolism and stress management.

• B5 (pantothenic acid): Crucial for cortisol production
• B6: Helps with neurotransmitter balance and mood
• B12: Supports energy, brain function, and red blood cell production

 Look for a methylated B-complex for better bioavailability.

 Magnesium

Often called the “calm mineral,” magnesium helps relax the nervous system, balance cortisol, and support deep sleep.

• Regulates the HPA axis (your stress response system)
• Eases anxiety, tension, and irritability
• Supports muscle relaxation and sleep

Best forms: Magnesium glycinate or magnesium threonate (for brain/mood support)

Licorice Root (Deglycyrrhizinated or DGL)

Licorice can help extend the half-life of cortisol, offering support for those with very low cortisol levels. However, not ideal for those with high blood pressure or elevated cortisol.

• Helps sustain energy
• Supports adrenal recovery in depleted phases
• Combine with adaptogens for better results

 Use short-term under guidance if you have blood pressure concerns.

 Phosphatidylserine

This unique fat compound helps modulate high cortisol levels, especially when stress is interfering with sleep or causing weight gain around the belly.

• Lowers evening cortisol spikes
• Supports memory and cognitive clarity
• Ideal for people with “wired but tired” insomnia

Best taken in the evening if cortisol is elevated at night.